$$\mbox{trace} (\Delta F) \leq 0 $$
where
$$\Delta = \frac{A^{-1}}{\alpha} \bigg( \Lambda \Lambda^T - 2 \alpha \Lambda_{symm} \bigg) \frac{A^{-1}}{\alpha} $$ $$ \Lambda = (c^T c) A^{-1}$$ $$ 0 \neq \alpha = 1 + c A^{-1} c^T \in \mathbb{R}$$
$A$ is a (symmetric) positive definite matrix and $c$ is a row vector with only one non-zero entry. And $F$ is a diagonal matrix with non-negative entries. $\Lambda_{symm}$ is the symmetric part of $\Lambda$
Testing this via numerics verify this claim (though $\Delta$ has positive eigenvalues at times); however, I can't prove it. Any help/advice on how to go about proving this would be much appreciated.
The inequality is false. It is equivalent to the statement that $\Delta$ has a nonpositive diagonal. Here is a counterexample. Consider $$ A^{-1}=\pmatrix{3&-1&3\\ -1&5&4\\ 3&4&9}, \ c^T=\pmatrix{1\\ 0\\ 0}, \ \Lambda=\pmatrix{3&-1&3\\ 0&0&0\\ 0&0&0}. $$ Then $\alpha=4$ and $\det A^{-1}=9$. Sylvester's criterion shows that $A^{-1}$ and in turn $A$ are positive definite. Straightforward calculations show that $$ \Delta = \frac1{16}\pmatrix{-285&-29&-441\\ -29&51&23\\ -441&23&-597}. $$ Therefore the trace of $\Delta F$ is positive when $F$ is equal to or close to $\operatorname{diag}(0,1,0)$.