A look at the first few zeros $$14.134725,21.022040,25.010858,30.424876,32.935062,37.586178,\dots$$ is in accord with
Numerical evidence suggests that all values of $t$ (the imaginary part of a root of $\zeta$) corresponding to nontrivial zeros are irrational (e.g., Havil 2003, p. 195; Derbyshire 2004, p. 384).
(numbers and quote taken from here). What are the attempts to prove that all values of $t$ are irrational? Would it mean something to the distribution of primes, if one, some or plenty of rational roots $\frac{1}{2}+i\frac{q}{r}$ exist?
Actually, the rationality or irrationality of the Riemann zeros does have subtle influence on the distribution of primes. In analytic number theory, this sub-subject goes under the name 'Oscillation Theorems'. An example can be found in the (excellent) book "Multiplicative Number Theory" by Montgomery and Vaughan. Corollary 15.7 says that if the ordinates $\gamma>0$ of the Riemann zeros are linearly independent over $\mathbb Q$, then $$ \limsup_{x\to\infty}\frac{M(x)}{x^{1/2}}=+\infty $$ and $$ \liminf_{x\to\infty}\frac{M(x)}{x^{1/2}}=-\infty. $$ Here $M(x)$ is the summatory function of the Möbius $\mu$ function: $$ M(x)=\sum_{n<x}\mu(n). $$ The connection is, of course, the explicit formula.
Edit: As a second example, Rubinstein and Sarnak show (roughly speaking) that under the Riemann Hypotheis and the assumption the zeros are linearly independent over $\mathbb Q$, that $$ \lim_{x\to\infty}\frac{1}{\log(x)}\sum_{\substack{n<x\\\pi(n)\ge \text{Li}(n)}}\frac{1}{n}=0.00000026 $$ as well as other results, in their paper Chebyshev's Bias.