Given a topological space $X$, a point $x_0 \in X$ and an open cover $\mathcal{U}$ of $X$ of path-connected subsets containing $x_0$ which is closed under finite intersections, we have by Van-Kampen $$ \pi_1(X,x_0) = {\text{colim}}_{U \in \mathcal{U}} \bigl(\pi_1(U,x_0)\bigr). $$
Is there a counter example in which all requirements are satisfied except "closed under finite intersection"?
As a concrete and (to my mind at least) particularly bad example: Take $X = B(0,2) \subset \mathbb{R}^2$ the ball of radius 2 in the plane $U_1 = X - \{0\}$ and $U_2 = B(0,1)$. Then without accounting for the role of intersection, we would expect $\pi_1(B(0,2), (1/2,0)) \cong \mathbb{Z}$, while the full space is obviously contractible.