Let $C\neq\emptyset$ be a set of infinite cardinals with the property that NO member of $C$ occurs as the supremum of strictly smaller members of $C$. So the cardinals in $C$ are sort of "isolated".
I am wondering if there is a name for such sets somewhere in literature, and where in mathematics they occur "naturally", if at all.
Maybe you are looking for successor cardinals. They are all regular, so cannot be written as the sup of any smaller set. By contrast limit cardinals like $\aleph_\omega$ can be written as the sup of smaller cardinals. It doesn't seem natural to consider sets like your $C$, as $\aleph_\omega$ could be in it as long as there are only finitely many smaller cardinals in the set.