Clearly $\emptyset \subset A$ where $A$ is any set. But does that mean $\emptyset \in A$? And if so, would it make sense to try to perform arithmetic operations with it. Like
$$\emptyset \cdot 5 \tag{where $5 \in A$}$$
This is inspired by a question that was along the lines of: if a relation is symmetric and transitive, is it reflexive? Where I've seen (and am relatively satisfied by) the answer of: no, consider the empty relation.
Normally $\emptyset$ is not a number. Multiplication is defined between two numbers. Hence it is equally as meaningful to write $\emptyset \cdot 5$, as it is to write $banana \cdot 5$. They mean nothing on their own, but we can always assign meaning to them.
However, there is an important exception. In a common construction of natural numbers, due to Zermelo and Fraenkel, everything a set: there are no separate "non-set" numbers. The number zero is defined as the empty set, the number one is defined as the set containing the empty set. And so on, as described in the link. In this construction, it is meaningful to write $\emptyset\cdot 5$, because this translates to just $0\cdot 5=0$.