I need to find possible values of $k$ with $k \in \mathbb{N}$ such that for any $n \in \mathbb{N}$ the equation $2^k n^2 + 2^k n + 1$ will never be a perfect square.
So, I thought, maybe for even $k$ I get solutions because then it is possible to complete the square, like:
Let be $k = 2m; \quad m \in \mathbb{N}$
\begin{align} 2^{2m} n^2 + 2^{2m} n + 1 &= (2^m)^2 n^2 + 2 \cdot 2^{m} \cdot 2^{m-1} n + 1 \\ &= \left(2^m n + 1\right)^2 + 2^{m+1} \left(2^{m-1} - 1 \right) n \\ &= \left(2^m n + 1\right)^2 + \left(2^{m}\right)^2 n - \left(2^m\right) n \end{align}
But then I am stuck and don't know if it leads me to something.
Edit 1:
The comment of Shamim leads me to the condition that if it is a perfect square, it needs to be an odd one because:
\begin{align} 2^k n^2 + 2^k n + 1 \equiv 1 \mod{4} \end{align}
But still, it does not restrict $k$.
I'll assume you question is about values of $k$ and $n$ that makes $2^kn^2+2^kn+1$ never to be a perfect square, where $k,n \in N$
We know that if $z$ is a perfect square, then $z^2+1$ cannot be a perfect square, this is the definition you'll use to solve your problem
$2^kn^2+2^kn+1 = 2^k\cdot(n^2+n)+1 = 2^k\cdot{n}\cdot(n+1)+1$
Now say $k=2m$ and $n=p^2$
$2^{2m}\cdot{p^2}\cdot(p^2+1)+1$
$( 2^m\cdot{p} )^2\cdot(p^2+1)+1$
Now if $p^2+1$ is a perfect square, then that expression can never be a perfect square
So we have to find the value of $p$ and $m$ that makes $p^2+1$ perfect, but $p^2+1$ cannot be a perfect square as we've shown earlier, since it can't be a perfect square then our expression is likely a perfect square if $k=2m$, meaning if $k$ is even and if $n=p^2$, meaning if $n$ is perfect, otherwise our expression is cannot be a perfect square
$2^kn^2+2^kn+1$ cannot be a perfect square, if $k$ is odd and $n$ is a perfect square