Suppose a large number of N people flip a coin 100 times, how would you find the percentage of them that would get less than 45 heads?

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Assume that the probability of 100 people is big enough that the trial can be approximated by normal distribution.

In the problem, N is unknown.

I think you would need to use the 68-95-99.9 rule, but I'm not sure exactly how/what formula I would use. Help is appreciated. Thanks!

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Let $X$ denote the number of heads we obtain in $100$ flips.

Normal approximation without continuity correction:

$$\mu=np$$

$$\sigma^2=npq$$

where $$\frac{X-\mu}{\sqrt{npq}}\sim N(0,1)$$

Then we have

$$\begin{align*} P(Z\lt 45) &=\Phi\left({\frac{45-50}{\sqrt{100\cdot0.5\cdot0.5}}}\right)\\\\ &=\Phi(-1)\\\\ &\approx0.1587 \end{align*}$$

With continuity correction:

$$\begin{align*} P(Z\lt 45) &=\Phi\left({\frac{44.5-50}{\sqrt{100\cdot0.5\cdot0.5}}}\right)\\\\ &=\Phi(-1.1)\\\\ &\approx0.1335 \end{align*}$$

Exact probability using binomial distribution:

$$\begin{align*} P(X<45) &=\sum_{k=0}^{44} {n\choose k}{0.5^ k}{0.5^{n-k}}\\\\ &=\sum_{k=0}^{44} {100 \choose k}{0.5^ k}{0.5^{100-k}}\\\\ &=0.1356265 \end{align*}$$

This can be calculated in R:

> sum(dbinom(0:44,100,.5))
[1] 0.1356265