I remember when I was in Moscow one of my homework questions was:
Is there a $2\times 4$ matrix whose $2\times 2$ minors are:
a) $(2,3,4,5,6,7)$
b) $(3,4,5,6,7,8)$
c) $(5,6,7,8,9,10)$
This problem is supposed to be an easy application of some basic result in multilinear algebra, but I still do not know how to solve it. I also want to ask the question for $n\times m$ matrix and $n\times n$ minors in general, for which we will have $\displaystyle C^{m}_{n}=\frac{m!}{n!(m-n)!}$ numbers to choose. I only know this is somehow related to intersection varieties, but the problem is really tiny, so there should be some easy solution of it.
The second problem, which appeared in my last year's final, was this:
Let $A$ and $B$ be two matrices with $m$ rows and $n\ge m$ columns. Prove that $$\det(AB^{t})=\sum_{I}\det A_{I} \det B_{I},$$ where the sum is running over all increasing sequences $I=(i_{1},i_{2},\dots,i_{m})\subset (1,2,\dots,n)$ and $A_{I},B_{I}$ mean $m\times m$-submatrices formed by $I$-columns.
This problem gives me the same feeling that it is supposed to be elementary and solvable by simple tools, but I could not unravel it via standard tools available. I feel there must be some better way to do it than expanding right side to equal the left side, etc. It has been one year and I still do not know how to solve it; so I decided to ask in here. This is from past exam so I think it is ok to ask online now.
For the second question, the formula is called the Cauchy-Binet formula, and the wikipedia page has a proof.
A higher level perspective which indicates how one might actually derive the formula is the following. Given a linear map $A:V\to V$, what is $\det(V)$? If we wedge $A$ together with itself $\dim V$ many times, we get a linear map $\bigwedge^{\dim V} A: \bigwedge^{\dim V}V\to \bigwedge^{\dim V}V$. However, since $\bigwedge^{\dim V}V$ is a one dimensional vector space, this map must be multiplication by a scalar. This scalar is $\det(A)$.
Because $V\mapsto \bigwedge^k V$ is functorial, if we have two linear transformations $A,B:V\to V$, we have that $\bigwedge^{\dim V} (AB)=(\bigwedge^{\dim V} A)(\bigwedge^{\dim V} B)$, and hence $\det(AB)=\det A \det B$.
What if we have a linear maps $A:V\to W$ and $B:W\to V$, and we want to compute $\det(BA)$? By functoriality, we have $\det(BA)=\bigwedge^{\dim V}(BA)=(\bigwedge^{\dim V} B)(\bigwedge^{\dim V} A)$. Thus, we need to understand $\bigwedge^{\dim V} B$ and $\bigwedge^{\dim V} A$.
Let $\dim V = m$ and $\dim W=n$ with $m\leq n$, and fix a basis of $V$ and $W$ so that $A$ and $B$ are given as matrices. Then we have a basis for $\bigwedge^{\dim V} W$ given by taking wedges of $m$ basis vectors of $W$, which is in correspondence with $m$ element subsets of $[n]=\{1,2,\ldots, n\}$. If $S\subset [n]$, we let $w_S$ be the corresponding basis vector. The coordinate of $\bigwedge^{\dim V} A$ corresponding to $w_S$ is exactly the minor coming from taking the columns from the set $S$. Something entirely similar happens with $B$.
We are left with two transformations $\mathbb{F}\to \mathbb{F}^{\binom{n}{m}} \to \mathbb{F}$, and we have that the coordinates of the transformations correspond to minors. Calculating the composition gives the formula.
For the first question, while Luboš Motl has already provided a good answer, there is some additional context to had. The map that sends an $m \times n$ matrix to it's minors is a form of the Plücker embedding, which embeds Grassmannians inside of projective space (and in particular shows that the Grassmannian is a projective variety).
Your particular case, which parameterized lines in $P^3$, is the prototypical example, and it is a classical result that the embedding is defined by a single quadratic relation (see the wikipedia page. The problem you have is to determine which of those particular points are on the quadric defined by the embedding.
If I had to guess, I would say that this is why you were assigned the problem and what you were supposed to get out of it.