0 68000 00027 7 is a UPC that the Hershey Company could use for some candy bar or other product. It happens that $6800000027$ is a prime number. But $68000000277$ is not. Likewise $6800000047$ is a prime number but quite obviously $68000000475$ is not. I'm sure that there exist GTIN-12 number that are prime which are also prime without the check digit, and maybe some of those numbers correspond to actual products you can buy at the supermarket or other store.
But what I want to know is this: what are the necessary (but not necessarily sufficient) conditions for such prime numbers?
Restating a comment, if I understand the gtin-12 algorithm correctly, the check digit $\ell$ in a 12-digit number $abc\ldots k\ell$ is determined by the congruence
$$3a+b+3c+\cdots+3k+\ell\equiv0\mod10$$
where the coefficients on the left alternate $3$ and $1$. This makes one necessary (but far from sufficient!) condition clear:
Beyond that I rather doubt there is any meaningful condition, beyond one that rules out $\ell=5$. Heuristically, there are $\pi(10^{11})\approx10^{11}/\ln(10^{11})$ 11-digit primes, so one would expect the number of 11- and 12-digit prime pairs to be something like
$${10^{11}\over\ln(10^{11})\ln(10^{12})}\approx1.43\times10^8$$
In particular, the denominator $\ln(10^{11})\ln(10^{12})\approx699.85$ suggests that one has a shot at finding such a pair by looking at around $700$ UPC labels. (Among the caveats, of course, is that manufacturers don't have a preference for 11-digit starting numbers that are even.)
Remark (added later): In terms of hunting for UPC labels that give prime pairs, the highlighted condition is really rather pointless. All you really need do is ignore any labels for which the last two digits are anything other than $1$, $3$, $7$, or $9$. The heuristic suggests that crowdsourcing the problem offers a reasonable chance of finding an actual prime-pair label: If a bunch of MSEers each look at a bunch of random products and run a primality test on the roughly $6$% that have a shot at being prime, someone might well find one. The aforementioned caveat, though, does seem to be a potential problem: As it happens, I have a shelf of CDs sitting handily behind me, but when I pulled a bunch down I found that the penultimate digit $k$ turned out to be a $2$ way more than a tenth of the time. I only found two labels that warranted testing. Needless to say, neither one produced a prime-pair example.