So I wanted to calculate
$$765_{18}- 210_{3}$$
First converting $765_{18}$ into decimal: $765_{18} = 2381_{10}$.
Then converting $2381_{10}$ into binary: $2381_{10} = 100101001101_2$
Now converting $210_3$ into decimal: $210_3 = 21_{10}$
Two-complement of $21_{10} = 101011_{2}$
So I now want to add $2381_{10} +(- 21_{10})$ in binary (I just add the binary of $2381_{10}$ with the two-complement of $21_{10}$):
$$ 100101001101_2 + 101011_2 = 100101111000_2$$
I should get $2360_{10}$, but instead, I get $2424_{10}$.
After a hint in the comment I realized that I had to use $12$ bits for $21_{10}$, i.e. $-21_{10} = 111111101011_2$
Now one only has to add both of these:
$$100101001101_2 + 111111101011_2 = 100100111000_2 = 2360_{10}$$