This question is arising from the answer to another one: How find this equation integer solution: $x^2y^2=4x^5+y^3$ . For $x < 27$ and $y > -243$ , the basic equation $x^2 y^2 = 4 x^5 + y^3$ is a function. By implicit differentiation we have found that: $$ y'(x) = \frac{20 x^4 - 2 x y^2}{2 y x^2 - 3 y^2} \quad \Longrightarrow \quad y'(0) = \; ? $$ From the picture it is suspected that: $y'(0) = 0$ , i.e. the slope of the tangent in $(x,y) = (0,0)$ may be zero. But I could not prove or disprove it. Any ideas?
Update.
When solving for $y$ (with help of MAPLE) we find something that looks like
a decent function, within a prescribed range e.g. $-1 < x < +2$ ; see picture.
(Bonus: integer solutions original question at red spots)
$$
y(x) = \left[\frac{\left(-54 x^2 + x^3 + 6 \sqrt{81 x^4 - 3 x^5}\right)^{1/3}}{3}
+ \frac{x^2}{3\left(-54 x^2 + x^3 + 6 \sqrt{81 x^4 - 3 x^5}\right)^{1/3}}
+ \frac{x}{3}\right] x
$$
So it's still not clear to me why the derivative $y'(0)$ would be somehow undefined.

A rather extreme close-up , namely $-1/10 < x < 1/10$ : picture on the right , doesn't reveal any other slope than zero at $(0,0)$ . Whiter means that the function $f(x,y) = 4 x^5 + y^3 - x^2 y^2\;$ is closer to zero; it is seen that $\;f(x,y)\;$ is very close to zero indeed in the neighborhood of $(0,0)$ , thus suggesting that the tangent may be ambiguous there. But is it?
My try. Draw a circle with radius $r > 0$ and $(0,0)$ as its midpoint: $$ x = r \cos(\phi) \qquad y = r \sin(\phi) $$ Substitute this into the basic equation $\;x^2 y ^2 = 4 x^5 + y^3\;$ and divide by $r^3$ : $$ 4 \cos^5(\phi)\, r^2 - \cos^2(\phi) \sin^2(\phi)\, r + \sin^3(\phi) = 0 $$ If $\;r \rightarrow 0\;$ i.e. becomes very small, then function values in the neighborhood of $\;(0,0)\;$ only depend on the last term $\;\sin^3(\phi)$ . Meaning that $\phi \approx 0$ or $\phi \approx \pi$ . The tangent through these two points has slope zero. Don't know if this counts as a proof.
All the issues here occur also with the simpler equation $x^5=y^3$. Indeed, just as the solutions to that equation can be parametrized as $(x,y) = (t^3,t^5)$, the solutions to the equation you ask about can be parametrized as $(t^3/(4-t)^2, - t^5/(4-t)^3)$. In both cases:
Over the real numbers, we can locally write $y$ as a function of $x$, and this function has a well defined first derivative. I get that $y = - \sqrt[3]{4} x^{5/3} - \frac{x^2}{3} + (\mbox{higher order terms})$.
The second derivative, $y''(x)$, does not exist. Intuitively, $y(x) \approx x^{5/3}$, then $y'(x) \approx x^{2/3}$ and then the second derivative blows up.
Over the complex numbers, for $x$ arbitrarily near $0$ but not equal to $0$, there are $3$ values of $y$ which satisfy the equation, so we can't write complex $y$ as a function of complex $x$ near $0$.
I would say that this curve has a well defined tangent, with slope $0$, over the reals, but not over the complexes. Whether or not you agree depends on exactly what definition of tangent line you are using.