Suppose we have a high-dimensional vector $\mathbf{u}\in\mathbb{R}^m$, which is drawn from a multivariate normal distribution $\mathbf{u}\sim\mathcal{N}(\mathbf{\mu}, \mathbf{\Sigma})$. To approximate the mean of the elements of $\mathbf{u}$ ($\bar{\mathbf{u}} = \frac{1}{m}\sum_{i=1}^m u_i$), we can sample $n<m$ elements of $\mathbf{u}$, sum them up, and then divide the sum by the number of samples $n$:
$$\bar{\mathbf{u}} \approx \hat{\bar{\mathbf{u}}} = \frac{1}{n} \sum_{i\in\text{sample}} u_i.$$
We can expect the approximate mean $\hat{\bar{\mathbf{u}}}$ to change if we sample a different set of $n$ elements. What is the variance of the approximate means?
Example:
$$\mathbf{u} = [1, 2, 3]^T$$
The mean of the elements of $\mathbf{u}$ is $\bar{\mathbf{u}} = \frac{1}{3}(1+2+3) = 2$. We can approximate $\bar{\mathbf{u}}$ by sampling just two elements of $\mathbf{u}$:
$$\hat{\bar{\mathbf{u}}} = \frac{1}{2}(1+2)=1.5$$
We can sample a different set of elements:
$$\hat{\bar{\mathbf{u}}} = \frac{1}{2}(1+3)=2$$
We are looking for the variance of $\hat{\bar{\mathbf{u}}}$, where $\mathbf{u}$ is a high-dimensional vector drawn from a multivariate normal distribution, $\bar{\mathbf{u}}$ is the mean of the elements of $\mathbf{u}$, and $\hat{\bar{\mathbf{u}}}$ is an estimate of $\bar{\mathbf{u}}$.
I think you're asking what is $\text{Var}[\mathbf{\bar{u}}]=\text{Var}\left[\frac{1}{n}\sum\limits_{i=1}^{n}\mathbf{u}_i\right]$, where $\mathbf{\bar{u}}=\hat{\pmb{\mu}}$.
Can you use the following property of variance to help solve your problem: for $a \in \mathbb{R}$, $X,Y$ independent random variables, we have $\text{Var}[aX+Y]=a^{2}\text{Var}[X]+\text{Var}[Y]$?