When writing a mathematical model for non-mathematical audiences, how do you begin a sentence defining a variables and parameters?

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Say you are writing a mathematical modeling paper in a science journal. How do you write your variable and parameter definitions in paragraph form so that you keep active voice but do not sound repetitive. For example

"$x$ is the average rate of change of ..."

Variable name followed by "is" sounds correct, but this must be frowned upon due to capitalization issues. Perhaps you could write,

"The average rate of change of ... is [called] $x$"

This is passive voice. We tend to use in proofs,

"Let $x$ be the rate of change of ..."

But this gets repetitive fast if you are writing in paragraph form. My guess is that this is more of an issue for applied mathematicians writing for non-math audiences.

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Repetition is actually not that bad. It certainly is better than elegant variation. A collection of all the typical linguistic constructions used in mathematics can be found in Jerzy Trzeciak's Writing Mathematical Papers in English.

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One of the great things about the English language is that there are so many different ways to say the same thing. So, avoiding repetitiveness should not be too difficult. Here are a few different ways to phrase your example sentence:

(1) Let $x$ be the rate of change ...

(2) Using $x$ to denote the rate of change, ...

(3) Let's use $x$ to represent the rate of change ...

(4) If $x$ is the rate of change, then ...

And, of course, you can get other variants by putting this clause later in the sentence:

(5) We will show that $y = kx$, where $x$ is the rate of change ...

And so on. Bear in mind that this sort of flexibility is often a source of confusion for readers whose native language is not English. If we use different words, this suggests to them that the meaning might be somehow different, too. There is a nagging fear, for example, that "denote" and "represent" might have two different meanings. For this audience, repetition is good, sometimes. So, don't go overboard with the thesaurus.