The first limit is $$\lim_{(x,y) \to (0,0)} \frac{\partial^2}{\partial y \partial x} \frac{x^3 y -x y^3}{x^2 +y^2},$$ computed by
(%i17) limit(diff(diff((x^3*y-x*y^3)/(x^2+y^2),x,1),y,1),(y,x),(0,0));
(%o17) -1
The second limit is $$\lim_{(y,x) \to (0,0)} \frac{\partial^2}{\partial x \partial y} \frac{x^3 y -x y^3}{x^2 +y^2},$$ computed by
(%i22) limit(diff(diff((x^3*y-x*y^3)/(x^2+y^2),y,1),x,1),(x,y),(0,0));
(%o22) 1
The CAS is Maxima.
Why do the two outputs differ? What does it result from?
Computation gives $$f_{xy}(x,y)={\partial^2\over\partial x\partial y}\left({x^3y-xy^3\over x^2+y^2}\right)={(x^2-y^2)(x^4+10 x^2 y^2+y^4)\over (x^2+y^2)^3}\ ,$$ valid for $(x,y)\ne(0,0)$. Here the right hand side is constant on rays $$r\mapsto (x,y):=r(\cos\phi,\sin\phi)\qquad(r>0)\ ,$$ namely equal to $$g(\phi):=\cos(2\phi)\bigl(\cos^4\phi+10\cos^2\phi\sin^2\phi+\sin^4\phi\bigr)\ .$$ One has $g(0)=1$ and $g(\pi/2)=-1$; therefore $f_{xy}$ is discontinuous at $(0,0)$. This leads to different values for the two limits taken in different orders.