If we consider the numbers ${2n \choose n}/2 $ for $n$ small:
[ 1, 1 ][ 2, 3 ][ 3, 10 ][ 4, 35 ][ 5, 126 ][ 6, 462 ][ 7, 1716 ][ 8, 6435 ] [ 9, 24310 ][ 10, 92378 ][ 11, 352716 ][ 12, 1352078 ][ 13, 5200300 ] [ 14, 20058300 ][ 15, 77558760 ][ 16, 300540195 ]
we observe that ${2n \choose n}/2 $ is odd if and only if $n$ is a power of $2$.
We can easily check with a computer that it is true for $n \le 2^{10}$, so that we can expect it is true in general.
Question: What's the proof?
[I'd love to see a combinatorial argument.]
More generally, if $d$ is the largest integer such that $2^d$ divides $\binom{2n}{n}$, then $d$ is the number of non-zero binary digits of $n$.
There is a general formula for the highest power of a prime $p$ that divides $m!$:
$$\sum_{k=1}^{\infty}\left\lfloor\frac{m}{p^k}\right\rfloor$$
So the number of powers of $2$ that divide $\binom{2n}{n}=\frac{(2n)!}{n!n!}$ is:
$$\sum_{k=1}^{\infty} \left(\left\lfloor\frac{n}{2^{k-1}}\right\rfloor -2\left\lfloor\frac{n}{2^k}\right\rfloor\right)$$
Every term here is positive because $\lfloor 2x\rfloor - 2\lfloor x\rfloor\geq 0$.
When $2^{k-1}\leq n<2^k$, we get a term of $1$ in this sum.
When $n=2^{k-1}$ this is the only non-zero term in this sum.
Now, if $\frac{n}{2^{k-1}}$ is an integer and odd, then the $k$th term is again $1$. The only way for the sum to be $1$ is if these two terms are the same.
What you can actually show is that the $k$th term in this sum is the $(k-1)$th binary digit of $n$.
There ought to be some combinatorial argument. We can see that $\binom{2n}{n}$ is divisible by $2$ combinatorially by using the complement function on the $n$-subsets of $\{1,2,\dots,2n\}$. Is there another action of order $2$ we can find which commutes with this one if $n$ is not a power of $2$?