Hi I was reading topology without tears appendix 1 :
This made sense at first as you can always just take the power-set. But can't you really construct a largest cardinal number? The operation of taking power-set is monotonic on an infinite set. Couldn't you encounter an aleph fixpoint (isn't one assured to exist because of Knaster-Tarski theorem) which would be the largest cardinal number? Or am I plain wrong. Thanks in advance.

There are Aleph fixed points, but they're not a largest cardinal. By Hartogs' theorem, for a every cardinal, there's a larger cardinal. This dates back to 1915. Of course, as mentioned, by the power-set axiom and Cantor's earlier theorem it was already known that for any cardinal there's a larger cardinal. Hartogs obtained the result using well-orders.
The lowest Aleph fixed point $\lambda$ is $$\alpha_0 = \omega_0\quad \alpha_{n+1}=\omega_{\alpha_n}\quad \lambda = \lim_{n\rightarrow \omega_0} \alpha_n$$ Then $\lambda = \omega_\lambda = \aleph_\lambda$, but $\lambda$ is not very big. It has cofinality $\operatorname{cf} \lambda =\aleph_0$ because it's the limit of a $\omega_0$-indexed sequence.
A cardinal $\kappa$ is called weakly inaccessible if $\kappa = \operatorname{cf}\kappa = \aleph_\kappa$. These are already big enough that their existence isn't provable in ZFC.
A cardinal $\kappa$ is called strongly inaccessible if $\kappa = \operatorname{cf}\kappa = \aleph_\kappa = \beth_\kappa$. Again, their existence isn't provable in ZFC, but if they exist they're impressive. Because then $V_\kappa$ is a model of ZFC, where $V_\kappa$ is from the von-Neumann hierarchy. In this model built from a set inside the model, $\kappa$ serves as the proper class of ordinals of $V_\kappa$. So thinking about it externally, you can think of the proper class $\text{Ord}$ of all ordinals of a model as a kind of 'largest cardinal', but it's not a set, not an ordinal of the model in the regular sense.