Let $x,y,z>0$. Prove that: $$3\geq \frac{(x+ y)^{2}x^{2}}{(x^{2}+ y^{2})^{2}}+ \frac{(y+ z)^{2}y^{2}}{(y^{2}+ z^{2})^{2}}+ \frac{(z+ x)^{2}z^{2}}{(z^{2}+ x^{2})^{2}}$$
I need to the hints and hope to see the Buffalo Way help here! Thanks a lot!
My idea is as follows: Because this inequality is cyclic. So, it's enough to prove this inequality in two cases: $x\leq y\leq z$ and $x\geq y\geq z$. I can prove it with $x\leq y\leq z$ but with $x\geq y\geq z$, I can't.
Remark: Let us describe simply a known trick for the problem of proving $f(u)+f(v)+f(w)\ge 0$ under constraint $uvw=1$ and $u, v, w > 0$.
The method of Lagrange multipliers yields the system of equations \begin{align} f'(u) &= \lambda vw, \\ f'(v) &= \lambda uw, \\ f'(w) &= \lambda uv,\\ uvw &= 1.\tag{1} \end{align} Clearly, we have $uf'(u) = vf'(v) = wf'(w) = \lambda$. If the equation $xf'(x) = c$ has at most two distinct positive real solutions for any $c \in \mathbb{R}$, then two of $u, v, w$ are equal.
This trick is useful for many problems. For example,
Example 1: Let $a, b, c$ be positive real numbers such that $abc=1$. Prove that $$\frac{a}{a^{11}+1} + \frac{b}{b^{11} + 1} + \frac{c}{c^{11}+1} \le \frac{3}{2}.$$
Example 2: Let $a, b, c$ be positive real numbers such that $abc=1$. Prove that $$\frac{7-6a}{2+a^2} + \frac{7-2b}{2+b^2} + \frac{7-2c}{2+c^2} \ge 1.$$
Example 3: Let $a, b, c$ be positive real numbers such that $abc=1$. Prove that $$\frac{1}{a+3} + \frac{1}{b+3} + \frac{1}{c+3} \ge \frac{a}{a^2+3} + \frac{b}{b^2+3} + \frac{c}{c^2+3}.$$
Example 4: Let $a, b, c$ be positive real numbers such that $abc=1$. Prove that $$\frac{1}{a+4} + \frac{1}{b+4} + \frac{1}{c+4} \ge \frac{a}{a^2+4} + \frac{b}{b^2+4} + \frac{c}{c^2+4}.$$
Example 5: Let $a, b, c$ be positive real numbers such that $abc=1$. Prove that $$\sum_{\mathrm{cyc}} \sqrt{\frac{a}{a+8}} \ge 1.$$
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Use this trick for the OP:
Equivalent problem (as @Display name pointed out): Let $u, v, w > 0$ with $uvw=1$. Prove that $$\frac{(1+u)^2}{(1+u^2)^2}+\frac{(1+v)^2}{(1+v^2)^2}+\frac{(1+w)^2}{(1+w^2)^2}\leq 3.$$
Let $f(x) = 1 - \frac{(1+x)^2}{(1+x^2)^2}$. We need to prove that $f(u)+f(v)+f(w)\ge 0$. The method of Lagrange multipliers yields the system of equations \begin{align} f'(u) &= \lambda vw, \\ f'(v) &= \lambda uw, \\ f'(w) &= \lambda uv, \\ uvw &= 1. \end{align} Clearly, we have $uf'(u) = vf'(v) = wf'(w) = \lambda$. Let us prove that if $(u, v, w, \lambda)$ with $u, v, w > 0$ satisfies the above system of equations, then two of $u, v, w$ are equal.
Let $F(x) = xf'(x) = \frac{2x(1+x)(x^2+2x-1)}{(x^2+1)^3}$.
Clearly, $F(0) = 0$, $F(\sqrt{2}-1) = 0$, $F(x) < 0$ on $(0, \sqrt{2}-1)$, and $F(x) > 0$ on $(\sqrt{2}-1, +\infty)$.
We have $F'(x) = -\frac{2(2x^5+9x^4-14x^2-2x+1)}{(x^2+1)^4}$. Let $G(x) = 2x^5+9x^4-14x^2-2x+1$. From Descartes' sign rule, since there are two sign changes, $G(x) = 0$ has at most two positive real roots. Also, we have $G(0) > 0$, $G(\sqrt{2}-1) = 32-24\sqrt{2} < 0$ and $G(+\infty) = +\infty$. Thus, $G(x) = 0$ has exactly one real solution on $(0, \sqrt{2}-1)$ and $(\sqrt{2}-1, +\infty)$, respectively. Thus, $F'(x) = 0$ has exactly one real solution on $(0, \sqrt{2}-1)$ and $(\sqrt{2}-1, +\infty)$, respectively.
Figure of $F(x)$:
Thus, $F(x) = c$ has at most two distinct positive real solutions for any real number $c$. Since $F(u) = F(v) = F(w)$, we know that two of $u, v, w$ are equal.
For $u = v > 0$ and $w = \frac{1}{u^2}$, it is easy to prove that \begin{align} &f(u) + f(u) + f(\frac{1}{u^2})\\ =\ & \frac{(2u^{10}+4u^9+6u^8+4u^7+3u^6+2u^5+5u^4-u^2-2u+1)(u-1)^2}{(u^2+1)^2(u^4+1)^2}\\ \ge & 0. \end{align} Thus, the inequality is true for $u, v, w > 0$ satisfying the system of equations (1).
It remains to prove that the inequality is true if $\min(u, v, w) \to 0^{+}$ (meaning $(u,v,w)$ approaches the boundary of the constraint).
Let $H(x) = \frac{(1+x)^2}{(1+x^2)^2}$. It is easy to prove that $H(x) \le \frac{147}{100}$ for all real numbers $x$. Note also that $H(x) \le \frac{3}{100}$ for $x \ge 10$. Thus, if $\min(u, v, w) \to 0^{+}$, then $H(u) + H(v) + H(w) \le \frac{147}{100} + \frac{147}{100} + \frac{3}{100} = \frac{297}{100}$. The desired result follows.
We are done.