After lengthy calculations, I arrived at \begin{align*} \int_1^\infty x^a (x-1)^b e^{cx}dx, \end{align*} which cannot be solved in closed-form. I thus seek to approximate the integral, potentially including special functions. The constants $a,b,c$ may be complex but are chosen such that the integral exists.
Any ideas how to approximate the integral? I thought of rounding the real and imaginary part of $a$ and $b$ to integers. Then, simplifying the first two terms and plenty of partial integrations should give a solution. But that seems to be a very naive idea.
Your integral after substituting $x=z+1$ (and replacing $c$ by $-c$ with $c>0$) becomes $$e^{-c} \int_0^\infty (z+1)^a z^b e^{-cz} \, {\rm d}z = e^{-c}\Gamma(b+1) U(b+1,a+b+2,c) \, .$$ The LHS can be calculated explicitly if $a$ is an integer, since then it becomes - after using the binomial theorem on $(z+1)^a$ - a finite sum $$\frac{e^{-c}}{c^{b+1}} \sum_{n=0}^a \binom{a}{n} \frac{(b+n)!}{c^n} \, .$$
In general however, the second Kummer solution $U$ can be quite complicated and as you are mentioning approximations, have you tried to deploy the saddle-point method i.e. $$\int_0^\infty (z+1)^a z^b e^{-cz} \, {\rm d}z = \int_0^\infty e^{-\left\{cz-a\log(z+1)-b\log(z)\right\}} \, {\rm d}z$$ and then expanding the power $$f(z)=cz-a\log(z+1)-b\log(z) \approx f(z_+) + \frac{f''(z_+)}{2} (z-z_+)^2$$ about its minimum $z_+$? For complex $a,b,c$ with $\Re(c)>0$ the contour $(0,\infty)$ can be deformed to go through that minimum/saddlepoint which is given by one of the solutions $$z_\pm = \frac{a+b-c \pm \sqrt{(a+b-c)^2 + 4bc}}{2c}$$ of $$f'(z)=c-\frac{a}{z+1} - \frac{b}{z} =0 \, .$$ I picked the solution that naturally lies on $(0,\infty)$ for positive parameters. The saddlepoint method then gives the approximation $$\int_0^\infty (z+1)^a z^b e^{-cz} \, {\rm d}z \approx e^{-f(z_+)} \sqrt{\frac{2\pi}{f''(z_+)}} = (z_+ + 1)^a z_+^b e^{-cz_+} \sqrt{ \frac{2\pi}{\frac{a}{(z_+ + 1)^2} + \frac{b}{z_+^2}} }$$ off only about 1-2 percent.