Consider a field field $\mathbb{F}$ and a function $f:\mathbb{F}^n\rightarrow\mathbb{F}$. Let $P$ be the set of all polynomials that agree with $f$ on all inputs, that is, $P=\{p:\forall x\in\mathbb{F}^n,p(x)=f(x)\}$. Because there always exists some n-variate polynomial $p$ such that $p(x) = f(x)$, we know that $P\neq\emptyset$. Therefore we can define a set $L$ consisting of all elements of $P$ with lowest degree, that is, $L=\{p\in P:\forall q\in P,deg(p)≤deg(q)\}$.
Must it be the case that $|L|=1$?
Here is my attempt at proving so:
Assume $p,q$ are different polynomials, both of lowest degree $d$. Their difference is a polynomial of degree $d$ or lower, and as a function, takes all elements of $\mathbb{F}^n$ to $0$. I'm not sure what to do next.
NOTE
If it is possible for there to be multiple polynomials of lowest degree, (equivalently, $|L|>1$), I would be interested in knowing for which finite fields and values of n this is the case.
We assume that the field $\Bbb F$ is finite and $|\Bbb F|=q$. Litho’s example shows that it can happen that $|L|>1$.
On the other hand, we can achieve an uniqueness of polynomials of $L$, imposing a natural restriction on their degrees. Indeed, given $f$, by induction with respect to $n$ we can construct a multidimensional Lagrange interpolation polynomial for $f$, which has degree at most $q-1$ with respect to each variable (and so a total degree at most $(q-1)n$). It follows that the set $L$ is non-empty.
Since $x^q=x$ for each $x\in\mathbb F$, given any polynomial $p\in L$ represented as a sum of monomials, if we substitute, as orangeskid suggested, in each of the monomials a factor $x_i^{n_i}$ by $x_i^{m_i}$, where $m_i\in \{1,2,\ldots, q-1\}$, and $n_i\equiv m_i \mod (q-1)$, we obtain a reduced polynomial $\bar p$ which has degree at most $q-1$ with respect to each variable and $\bar p(x)=p(x)$ for each $x\in \Bbb F^n$.
For any polynomials $p,r\in L$, a polynomial $\bar p-\bar r$ has degree at most $q-1$ with respect to each variable. So it is zero by the following
Theorem (Combinatorial Nullstellensatz II). [A] Let $\Bbb F$ be a field and $f\in \Bbb F[x_1,\dots, x_n]$. Suppose $\deg f =\sum_{i=1}^n t_i$ for some nonnegative integers $t_i$ and the coefficient of $\prod_{i=1}^n x_i^{t_i}$ is nonzero. If $S_1,\dots, S_n\subset \Bbb F$ such that $|S_i| > t_i$ then there exists $s_1\in S_1,\dots, s_n\in S_n$ such that $f(s_1,\dots,s_n)\ne 0$.
References
[A] N. Alon, Combinatorial Nullstellensatz, Combinatorics, Probability and Computing 8 (1999), 7–29.
See (3) in this answer for more references.