I’d like to show that the fundamental group of $\mathbb{R}^3 \setminus \Delta$, where $\Delta$ is the line parametered by $t \rightarrow (0,0,t)$, is $\mathbb{Z}$.
To do so, I was thinking of using the map $\phi(\theta,r,z)=(r \cos(\theta),r \sin(\theta), z)$, which gives an homeomorphism (I think) between the topological space $U=S^1 \times ]0,+\infty[ \times \mathbb{R}$ and $\phi(U)=\mathbb{R}^3$. I was trying to calculate $\phi^{-1}(\mathbb{R}^3 \setminus \Delta)=U \setminus \phi^{-1}(\Delta)$ in the hopes of finding something whose fundamental group is $\mathbb{Z}$, but I couldn’t manage to do it yet. Could this approach work…?
Define $H:\Bbb{R}^{3}\setminus\Delta\times[0,1]\to\Bbb{R}^{3}\setminus\Delta$ given by $H((x,y,z),t)=(x,y,(1-t)z)$ then it is a deformation retract from $\Bbb{R}^{3}\setminus\Delta$ to $\Bbb{R}^{2}\setminus\{0\}$.
And we all know that $\Bbb{R}^{2}\setminus\{0\}$ is homotopy equivalent to the circle using the map $G:(\Bbb{R}^{2}\setminus\{0\})\times[0,1]\to \Bbb{R}^{2}\setminus\{0\} $ such that $G(x,t)=\frac{x}{1-t+t||x||}$ . Then this is a deformation retract to the unit circle.
This proves that $\Pi_{1}(A)\cong\Pi_{1}(D^{2}\setminus\{0\})\cong\Pi_{1}(S^{1})\cong\Bbb{Z}$ .
To see more visually, you can identify $\Bbb{R}^{3}$ with the open unit ball and use the same maps to deform it to $D^{2}\setminus\{0\}$ which deformation retracts to $S^{1}$.