Let $M$ be an $R$-module, where $R$ is a ring with unit. Given a ring automorphism $\phi: R \rightarrow R$, we can define a new $R$-module structure on $M$ by $r \cdot x = \phi(r) x$ for all $r \in R$, $x \in M$.
Can we find examples where this module induced by $\phi$ is not isomorphic to $M$? It seems that the two modules are at least in many ways similar, for example they have the same submodules.
I can see that they must be isomorphic if $M$ is free, since then any basis of $M$ is also a basis for the induced module. It is also clearly true for $\mathbb{Z}$-modules, since the only nontrivial ring automorphism of $\mathbb{Z}$ is $x \rightarrow -x$, and the inverse map is an automorphism of abelian groups.
Consider a field $F$ and the ring $R=F\times F$.
Let $M=\{0\}\times F$ with both the ordinary right $R$-module structure $(0,m)(r,s)=(0,ms)$, and let $M'$ be the same set with another $R$-module structure given by $(0,m)(r,s)=(0,mr)$.
This second structure is just given by the involution on $R$ given by $(r,s)\mapsto(s,r)$.
The annihilator in $R$ of $M$ is $ F\times \{0\}$ while the annihilator in $R$ of $M'$ is $\{0\}\times F$. Since isomorphic modules share annihilators, this shows $M\ncong M'$.