I would like to evaluate the following summation over two integer variables $n,m$
$$\sum_{n,m}(-1)^{nm}\delta(x-an-bm)$$
where $a,b\in\mathbb R$ can be any real number
Is there some way this could be simplified to only sum over one of the integer variables?
For any order of summation, your series will diverge in the sense of distributions: choosing an enumeration $n_j,m_j$ of the indices and a test function such that $\phi(0)\ne 0$
$$\lim_{J\to \infty} \langle \sum_{j=1}^J(-1)^{n_jm_j}\delta(x-a n_j +bm_j),\phi \rangle=\sum_{j=1}^\infty (-1)^{n_jm_j}\phi(a n_j +bm_j)$$ There are infinitely many $a n_j +bm_j$ arbitrary close to $0$, for those $j$ then $\phi(a n_j +bm_j)$ is arbitrary close to $\phi(0)$ so the series $\sum_{j=1}^\infty (-1)^{n_jm_j}\phi(a n_j +bm_j)$ has infinitely many terms of absolute value $>\frac12|\phi(0)|$.
I doubt you have any good reason to look at this kind of series.