These two definitions are from Topology, II Edition, James R. Munkres.
Definition 1.
A topology on a set $X$ is a collection $\mathfrak{I}$ of subsets of $X$ having the following properties:
$(1)$ $\emptyset $ and $X$ are in $\mathfrak{I}.$
$(2)$ The union of the elements of any subcollection of $\mathfrak{I}$ is in $\mathfrak{I}.$
$(3)$ The intersection of the elements of any finite subcollection of $\mathfrak{I}$ is in $\mathfrak{I}.$
If $X$ is a topological space with topology $\mathfrak{I},$ we say that a subset $U$ of $X$ is an open set of $X$ if $U$ belongs to the collection $\mathfrak{I}$
Definition 2
If $X$ is a set, a basis for a topology on $X$ is a collection $\mathscr{B}$ of subsets of $X$ (called basis elements) such that
For each $x∈X$, there is at least one basis element $B$ containing $x$
If $x$ belongs to the intersection of two basis elements $B_1$ and $B_2$, then there is a basis element $B_3$ containing $x$ such that $B_3⊆B_1∩B_2$.
If $\mathscr{B}$ satisfies these two conditions, then we define the topology $\mathfrak{I}$ generated by $\mathscr{B}$ as follows : A subset $U$ of $X$ is said to be open in $X$( i.e., to be an element of $\mathfrak{I}$ ) if for each $x\in U,$ there is a basis element $B\in \mathscr{B}$ such that $x\in B$ and $B\subset U.$
Suppose for a set $X$ I have a collection $\mathscr{B}$ satisfying the two properties mentioned in definition 2.
Now consider a subset $S$ of $X$ such that for each $x\in S,$ there is a basis element $B\in \mathscr{B}$ such that $x\in B$ and $B\subset S.$
Form $\mathfrak{I}_1$ such that we choose minimum number of $S_{\alpha}$ required so that $\mathfrak{I}_1$ forms a topology on $X.$
Now if I inject some more such subsets so that now $\mathfrak{I}_2$ is a topology on $X.$
Is such a scenario possible? I don't know , seems plausible to me. If that is the case . . .
does definition 2 say $\mathscr{B}$ is a base which "generates" multiple topologies on a set $X$?
Note that the definition for the topology generated by $\mathscr{B}$ is the set of all subsets $U$ of $X$ with the stated property. It follows that the topology generated is unique.