Fairly new to group actions and I'm having trouble finding answers to these in textbooks...
Say we have a primitive action of $G$ on $\Omega$, with regular elementary abelian socle $N$. Now suppose we have another set $\Delta$ which $G$ also acts on transitively.
First question: Is there any way of knowing if the action of $G$ on $\Delta$ is primitive without other information?
Second Question: Can we say $N$ acts regularly on $\Delta$?
The answer to your first question seems to be "no". The group $G = \operatorname{AGL}(2,3)$ is a primitive group of degree $9$ and order $432$. It also acts faithfully and transitively on the cosets of its Sylow $2$-subgroup $S$, but the action is not primitive, since $S$ is not a maximal subgroup of $G$.
Here is a Maple (17) session demonstrating this (which is how I found it in the first place):
(The last line shows that the maximal subgroups of $G$ all have order strictly greater than the order of $S$, so $S$ is not itself a maximal subgroup of $G$.)
This also shows that the answer to your second question is "no", since an Abelian transitive group is regular, and the degree here is the index $[G:S] = 27$, while the socle has order $9$.