Assume $A$ is a real (non-symmetric) positive definite matrix, that is, $$ x^T A x > 0 $$ for all real non-zero real $x$. It is easy to prove that the eigenvalues of $A$ have positive real part.
Conversely, assume $A$ is a (non-symmetric) real matrix, whose eigenvalues have positive real part. It does not necessarily follow that $A$ is positive definite. Nonetheless, does there exist a similar matrix $B$ which is positive definite? More precisely, does there exist an invertible matrix $P$ such that $P^{-1} A P$ is positive definite?
Here's a special case in which a complete answer may be given, and hopefully this leads to better understanding in the general case. We know that there is a real Jordan canonical form available for any real matrix. Suppose that the matrix leading to the Jordan canonical form of $A$ is real orthogonal. Then $A=O^{T}JO,$ where $J$ is the real Jordan canonical form, which means that $x^{T}Ax=(Ox)^{T}J(Ox)$ for all $x\in\mathbb{R}^{n}.$ Thus, the positive definiteness of $A$ is equivalent to that of $J$ in this case. Now if we inspect the Jordan blocks for some eigenvalue, we have four cases:
It should be clear that $J$ is positive definite if and only if all blocks are of types (1) and (3).