Looking at Ribenboim's book, page 2.
First question: What is the difference in the notational use of $X, Y, Z$ versus $x, y, z$?
Second question: Why is this true: "If $n$ is odd then $X^n + Y^n = Z^n$ has a non-trivial solution if and only if $X^n + Y^n + Z^n = 0$ has a non-trivial solution."?
Upper-case letters are more variable than lower-case. The equation $X^n+Y^n=Z^n$ is to show the relationship among the variables. The lower-case letters $x,y,z$ indicate a specific solution.
$X$ is an indeterminate and $x$ is a number that gets plugged into it.
But really, you can ignore the difference.