Let $a,b$ be strictly positive constants and let $p\in(1/4,3/4)$. Is there $c>0$ such that
$$\int_0^1(1-t^a)^{1/2+p}[2t-(2+b)t^{b+1}]dt>c \quad ?$$
*The constant $c>0$ may depend on $a,b$ or $p$.
I tried several values for $(a,b,p)$, and always observed a positive integral. So, I'm conjecturing that the integral is strictly positive.
Intuitively, $2t-(2+b)t^{b+1}$ is a concave function on $[0,1]$ which is weighted by a factor $(1-t^a)^{1/2+p}$. This factor is less than one, and decreases as $t\to 1$, and so it pushes the right tail of the function (which is negative) closer to zero. So it makes sense to think about a positive integral.
I wrote the integral in terms of Beta functions but didn't succeed.
$$\int_0^1 (1-t^a)^{1/2+p}[2t-(2+b)t^{b+1}]~dt$$ $$=\int_0^1 (1-t^a)^{1/2+p}~d(t^2-t^{b+2})$$ $$=\left.(1-t^a)^{1/2+p}(t^2-t^{b+2})\right|_0^1-\int_0^1(t^2-t^{b+2})(\frac 1 2+p)(1-t^a)^{p-1/2}(-at^{a-1})~dt$$ $$=0+\int_0^1(t^2-t^{b+2})(\frac 1 2+p)(1-t^a)^{p-1/2}(at^{a-1})~dt,\qquad (*)$$ which is positive. The latter integral is bounded by $$\max_{0\leq t\leq 1}(t^2-t^{b+2})\int_0^1(\frac 1 2+p)(1-t^a)^{p-1/2}\cdot at^{a-1}~dt=\max_{0\leq t\leq 1}(t^2-t^{b+2}),$$ where one uses the substitution $u=t^a$ for computing the last integral. It follows that when $b\rightarrow 0$, the integral approaches $0.$
By the above argument, there does not exist a uniform positive lower bound. However, one may still obtain a lower bound dependent on $a,b,$ and $p$:
Let $f(t)=t^2-t^{b+2}=t^2(1-t^b)\geq 0$. Then $f$ has a unique critical point at $t=\left(\frac 2{b+2}\right)^{1/b}$ in $(0,1)$ and $f$ is increasing on $[1/2,(2/(b+2))^{1/b}]$ (Note that $2^{b+1}>b+2$ for $b>0$ as can be checked by the fact that $g(x)=2^{x+1}-x-2$ satisfies $g(0)$ and $g'(x)>0$ for all $x\geq 0$). It follows from $(*)$ that $$\int_0^1 (1-t^a)^{1/2+p}[2t-(2+b)t^{b+1}]~dt$$ $$=\int_0^1 f(t)(\frac 1 2+p)(1-t^a)^{p-1/2}(at^{a-1})~dt$$ $$>\int_{1/2}^{(2/(b+2))^{1/b}} f(t)(\frac 1 2+p)(1-t^a)^{p-1/2}(at^{a-1})~dt$$ $$>f(1/2)\int_{1/2}^{(2/(b+2))^{1/b}} (\frac 1 2+p)(1-t^a)^{p-1/2}(at^{a-1})~dt$$ $$=\left[\left(\frac 1 2\right)^2-\left(\frac 1 2\right)^{b+2}\right]\cdot \left[\left.-(1-t^a)^{p+1/2}\right|_{1/2}^{(2/(b+2))^{1/b}}\right]$$ $$=\left[\left(\frac 1 2\right)^2-\left(\frac 1 2\right)^{b+2}\right]\cdot\left[\left(1-\left(\frac 1 2\right)^a\right)^{p+1/2}-\left(1-\left(\frac 2{b+2}\right)^{a/b}\right)^{p+1/2}\right],$$ hence a lower bound can be taken to be $$c(a,b,p):=\left[\left(\frac 1 2\right)^2-\left(\frac 1 2\right)^{b+2}\right]\cdot\left[\left(1-\left(\frac 1 2\right)^a\right)^{p+1/2}-\left(1-\left(\frac 2{b+2}\right)^{a/b}\right)^{p+1/2}\right]>0.$$