In $\frac{\overline{SIX}}{\overline{NINE}}=\frac23$ every letter denotes a UNIQUE digit,find $I$.
Expanding the fraction in base $10$ we have:
$300S+30I+3X=2020N+200I+2E$ , but this doesn't help much.We may deduce that since $\overline{SIX}\lt1000$ so $\overline{NINE}\lt1500$ , now we know $N=1$.How to find other digits specially $I$?
$$3\times\overline{SIX}=2\times\overline{NINE}$$
As you wrote, we have $N=1$. Also, we know that $X$ is even.
Let us separate it into cases. In the following, let $[n]$ be the right-most digit of $n$.
Case 1 : $X=0$. Then, $E=0,5$ from $[2E]=[3X]=0$. If $E=0$, then since the right-most two digits of $3\times\overline{IX}$ has to be $20$, we have to have $[3I]=2$ so $I=4$ which is sufficient. If $E=5$, then $[3I]=3$ so $I=1$ which is not sufficient since $1115$ is not a multiple of $3$.
Case 2 : $X=2$. Then, $E=3,8$. If $E=3$, then $[3I]=2$ so $I=4$. If $E=8$, then $[3I]=3$ so $I=1$ which is not sufficient.
Case 3 : $X=4$. Then, $E=1,6$. If $E=1$, then $[3I]=1$ so $I=7$ which is not sufficient. If $E=6$, then $[3I]=2$ so $I=4$.
Case 4 : $X=6$. Then, $E=4,9$. If $E=4$, then $[3I]=1$ so $I=7$ which is not sufficient. If $E=9$, then $[3I]=2$ so $I=4$.
Case 5 : $X=8$. Then, $E=2,7$. If $E=2$, then $[3I]=0$ so $I=0$ which is not sufficient. If $E=7$, then $[3I]=1$ so $I=7$ which is not sufficient.
Therefore, $\color{red}{I=4}$. $\left(\frac{940}{1410},\frac{942}{1413},\frac{944}{1416},\frac{946}{1419}\right)$
P.S. "every letter denotes a UNIQUE digit" then $\frac{942}{1413}$ is the only solution.