Find the sum of the series .

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The general term of the series is $\sum_{r=0}^{100}\binom{500}{r}\binom{500-r}{400}2^{100-r}$

What I tried to think that this series was an expansion for a series inside a series but the thing that i found out is that I have to find the sum of a series which stops at 100 but runs till the power of 500 .

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It is equal to $\sum_{r=0}^{100}\frac{500!}{r!(500-r)!}\frac{(500-r)!}{400!(100-r)!}2^{100-r}=\frac{500!}{400!100!}\sum_{r=0}^{100}\frac{100!}{r!(100-r)!}2^{100-r}={500\choose 100}3^{100}$.