I am pretty sure the following sum is zero:
$\sum_{i=0}^{\lfloor \frac{n+1}{2} \rfloor} \binom{n+2}{2 i +1}(4i-n)$
and have proven it to be zero for even $n$ (simply reverse the sum with variable substitution $i=n/2-j$ and then use the property that $\binom{n}{k}=\binom{n}{n-k}$ and show that the sum is equal to its negative.)
However I cannot figure out how to do the case where $n$ is odd. Mathematica seems to say that:
$\sum_{i=0}^{\lfloor \frac{n+1}{2} \rfloor} \binom{n+2}{2 i +1}(4i-n)=\frac{-2}{1+n} \binom{n+2}{1+2(1+\lfloor \frac{n+1}{2} \rfloor)}(1+\lfloor \frac{n+1}{2} \rfloor)(3+2\lfloor \frac{n+1}{2} \rfloor)$
but I have no idea what kind of identities or properties it is using to get that result.
Comment:
In (1) we split the sum conveniently.
In (2) we apply in the left sum the binomial identity $\binom{p+1}{q+1}=\frac{p+1}{q+1}\binom{p}{q}$ and in the right sum the binoimial identity $\binom{p+1}{q+1}=\binom{p}{q+1}+\binom{p}{q}$.
In (3) we collect equal summands.
In (4) we observe we can merge the left sum containing the even parts and the right sum which contains the odd parts of $(-1)^i\binom{2N}{i}$. Note that now the upper limit of the sum is $2N$.
In (5) we apply the binomial theorem.