I came across the following finite sum involving (generalized) binomial coefficients:
$$ 2^q \sum_{k=0}^r \binom{r}{k} \binom{k/2}{q} (-1)^k .$$
Putting this into Mathematica gives me:
$$ (-1)^q 2^{r-q} \left( \binom{2q-r-1}{q-1} - \binom{2q-r-1}{q} \right) $$
and I'm interested in how could this solution be derived. There seems to be some binomial coefficient magic going on which I don't understand.
So far I have made very little progress, I noticed that the $2^q \binom{k/2}{q} = \frac{1}{q!} \prod_{i=0}^{q-1} (k-2i)$ -term looks a bit like a double factorial but this didn't get me very far. There also seems to be a lot of identities for sums involving $ \binom{r}{k} (-1)^k $ but I haven't found anything useful for this case.
Since I am a Bear of Very Little Brain, and long proofs Bother me, let me post slightly shorter version of essentially the same proof.
$2^q\sum_{k=0}^r(-1)^k\binom rk\binom{k/2}q$ is the coefficient of $z^q$ in the expansion of $(1-\sqrt{1+2z})^r=\left(\frac{-2z}{1+\sqrt{1+2z}}\right)^r$.
Now we want to substitue $\sqrt{1+2z}$ by $1+w$. There is a purely algebraic lemma for this, but one way to establish it is to write this coefficient as a (complex) integral and apply the change of variables formula for integrals: \begin{multline} \DeclareMathOperator{\res}{res} %\res\,(1-\sqrt{1+2z})^r\frac{dz}{z^{q+1}}= \res\left(\frac{-2z}{1+\sqrt{1+2z}}\right)^r\frac{dz}{z^{q+1}}= (-2)^r\res\frac1{(1+\sqrt{1+2z})^r}\frac{dz}{z^{q-r+1}}=\\ (-2)^r\res\frac1{2+w}\frac{dw+w\,dw}{(w+w^2/2)^{q-r+1}}= (-1)^r2^{2r-q-1} \res\frac1{(2+w)^{q-r+1}}\frac{dw+w\,dw}{w^{q-r+1}}. \end{multline} (here $\res_z=\frac1{2\pi i}\oint_{|z|=\epsilon}$, if you will; since $z=w+w^2/2$, $dz=dw+w\,dw$).
So we get a sum of two binomial coefficients (each multiplied by $(-1)^\cdots2^\cdots$) — that's the answer Mathematica gave you.