I'm reading the paper "On the signature of four-manifolds with universal covering spin" By Peter Teichner, and at page 746 I got stuck in this passage:
The homotopy fibration $\tilde{M} \to M \to K(\pi, 1)$ induces an exact sequence in cohomology $$ 0 \to H^2(\pi; \mathbb{Z}_2) \to H^2(M;\mathbb{Z}_2) \to H^2(\tilde{M};\mathbb{Z}_2)$$
Where $M$ is a $4$-manifolds whose universal cover is spin, and whose fundamental group is $\pi$. The map $M \to K(\pi, 1)$ is the classifying map of the universal cover.
By homotopy fibration I mean (and I hope that the author used the same definition) the following:
DEF: $X→Y→Z$ is a homotopy fibration sequence if the composed map is a constant and the resulting map from $X$ to the homotopy fiber of $Y→Z$ is a weak homotopy equivalence.
I think something on the line of the Serre Exact sequence should work, but the indices are bothering me since the base space is $0$-connected, the fibre is $1$-connected and therefore the Serre Spectral Sequence should stop at $H^2(\pi; \mathbb{Z}_2)$.
The only possibility would be that the fact we are working in $\mathbb{Z}_2$ coefficient, permits us to do something more, but I do't know how.
Any help is appreciate
Have a look at John Klein's answer to this mathoverflow question. In your case, the base is $0$-connected and the fibration is $2$-connected, so you get a long exact sequence as desired (even integrally) and you may also add a term $H^3(\pi,\mathbb{Z}/2\mathbb{Z})$ at the end.