$$V_\pi(s) = E[R_t|s_t=s,\pi]$$
This is a value function for state s under policy $\pi$ where $R_t$ is the return value, all of which occurs at time t. I was wondering how I should read/ understand this, since from what I understand the E means expected value, but I have no clue how the inside of the brackets should be read.
The right hand side of the equation appears to read
The pipe in set notation means "such that", although here it reads more naturally as "assuming". I don't love the comma notation, but many authors use it in the set-builder context to mean the logical AND. So the literal reading would be "$R_t$ such that $s_t=s$ AND $\pi$"; then I tried to parse that based on your description of the left-hand side.