How many groups of 8 numbers can be formed from 45 lottery numbers, except a few rules.

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I'm trying to figure out how many groups of 8 lottery numbers can be formed from the set $A=\{1,2,3,\dotsc,45\}$. The first 3 numbers are "winning" numbers and the left over 5 "losing" numbers.

I understand that I need to figure out how many groups of 8 can be formed from 45 elements.

$$\binom{45}8 = \frac{45!}{8!(45-8)!}.$$

What I'm having a problem with is understanding how to take these rules into account.

Maybe something like:

$$\binom{45}3 * \binom{42}5?$$

To be honest I'm quite lost. All hints and pointers are appreciated.