Let W, X, Y, Z be subsets of {1, 2, . . . , 100} such that W ∩X = ∅, W ∩Y = ∅ and X ∩Y = ∅. Use the inclusion-exclusion principle to write down an expression for |W ∪ X ∪ Y ∪ Z|
Based on the question, I'm puzzled on what Z is as it is not mentioned in the question. How can you write an expression for |W ∪ X ∪ Y ∪ Z| when Z is not given?
$Z$ is mentioned in the question; it is one of the subsets. It doesn’t matter that we have no extra information about it, though, because we are just asked to write an expression for $|W \cup X \cup Y \cup Z|$ rather than actually compute its numerical value.
The inclusion-exclusion principle states, in this case, that
$$|W \cup X \cup Y \cup Z| = |W| + |X| + |Y| + |Z| - |W \cap X| - |W \cap Y| - |W \cap Z| - |X \cap Y| - |X \cap Z| - |Y \cap Z| + |W \cap X \cap Y| + |W \cap Y \cap Z| + |X \cap Y \cap Z| + |W \cap Y \cap Z| - |W \cap X \cap Y \cap Z| $$
In this case we know that $|W \cap X| = |W \cap Y| = |X \cap Y| = 0$ and so we in fact have
$$|W \cup X \cup Y \cup Z| = |W| + |X| + |Y| + |Z| - |W \cap Z| - |X \cap Z| - |Y \cap Z| + |W \cap X \cap Y| + |W \cap Y \cap Z| + |X \cap Y \cap Z| + |W \cap Y \cap Z| - |W \cap X \cap Y \cap Z| $$
We can remove any of the intersections that contain these intersections to give
$$|W \cup X \cup Y \cup Z| = |W| + |X| + |Y| + |Z| - |W \cap Z| - |X \cap Z| - |Y \cap Z| $$
If there is any more data in your question, you can use then this to make this expression more precise.