How do you show that $-1+(x-4)(x-3)(x-2)(x-1)$ is irreducible in $\mathbb{Q}$?
I don't think you can use the eisenstein criterion here
How do you show that $-1+(x-4)(x-3)(x-2)(x-1)$ is irreducible in $\mathbb{Q}$?
I don't think you can use the eisenstein criterion here
On
Actually, the obvious generalization is also true. Let $P$ and $Q$ be polynomial factors, so that the given expression equals $PQ$. Then $PQ=-1$ at each of the integer values, $1,2,3,4$ for this case. So $P,Q=\pm1$ at each of these integers, and whenever $P$ equals one, $Q$ equals minus one, and vice versa. But these are more than enough values to determine each polynomial, so $P=-Q$. But this is impossible because the coefficient of the highest order term in the product must be plus one.
On
Another argument, special to this polynomial.
Any number of arguments (including multiplying the thing out) show that the polynomial is $\equiv X^4-2\pmod5$. Thus in characteristic $5$, any root is a $16$-th root of unity. But the smallest field of characteristic $5$ whose cardinality is $\equiv1\pmod{16}$ is $\Bbb F_{625}$. Thus the polynomial is already irreducible over $\Bbb F_5$, thus over $\Bbb Z$, thus over $\Bbb Q$.
Using the Gauss lemma as suggested, note that $1,2,3,4$ are clearly not roots of $p(x)$. Also, when $x\leq 0$ or $x\geq 5$ we have $p(x)\geq -1+24>0$. So there are no integer roots. So $p$ is irreducible over $\mathbb{Z}$ and hence $\mathbb{Q}$.