How would I solve an IVP using Laplace transform if some initial values are not given?

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I have this IVP: \begin{align*} \dot{x}_1(t)&=\frac{f_3}{V_3}\,x_3(t)-\frac{f_1}{V_1}\,x_1(t)+f(t)\\ \dot{x}_2(t)&=\frac{f_1}{V_1}\,x_1(t)-\frac{f_2}{V_2}\,x_2(t)\\ \dot{x}_3(t)&=\frac{f_2}{V_2}\,x_2(t)-\frac{f_3}{V_3}\,x_3(t). \end{align*} In particular, take $f_i/V_i=0.001,\;i=1,2,3$ and let $f(t)=0.125\;\text{lb/min}$ for the first $48$ hours, thereafter, $f(t)=0.$ Use the Laplace transform to solve for $x_1(t).$

I don't know how to proceed with this problem. The examples shown in our class always give the initial value of the variable to look for and its derivative. How do I solve this problem if the initial value given is not the variable I'm looking for?

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Íf not stated explicitly differently, in this type of tasks all functions are zero at negative times, all inputs and reactions to them start only at time $t=0$. Usually this is expressed as $$x_k(0^-)=\lim_{t<0,\,t\to 0}x_k(t)=0.$$


The units given for the constants and function values do not match, if the $x_k$ are in [lb] and $t$ in [min], then the derivative matches with $f$, but $f_i/V_i$ should have unit [min$^{-1}$].