If $C_0, C_1, C_2,...,C_n$ are the binomial coefficients in the expansion of $(1+x)^n$, prove that: $$C_{r}.C_{n} + C_{r+1}.C_{n-1} +......+ C_{n}.C_{r} = C(2n, n+r) =\dfrac {(2n)!}{(n-r)! (n+r)!}$$
Is there any way to approach this sort of questions using calculus (derivatives or integration)?
THis suffices to differentiate $(1+x)^{2n}=(1+x)^n(1+x)^n $ $n+r$ times.
Differentiating the right side first,
By (General Leibniz rule), it's derivative is given by differentiating the first part $k$ times and the second part $(n+r)-k$ times.
It's derivative is given by $\sum_{k=0}^{n+r} {{n}\choose{k}}((1+x)^n)^{(k)}((1+x)^n)^{(n+r-k)}$
$=\sum_{k=0}^{n-r} {{n}\choose{k+r}} ((1+x)^n)^{(r+k)}((1+x)^n)^{(n-k)}$
Evaluating at $x=0$,
$=\sum_{k=0}^{n-r} \dfrac{(n+r)!}{(k+r)!(n-k)!} \dfrac{n!}{(n-r-k)!}\dfrac{n!}{k!}$
$=(n+r)! \sum_{k=0}^{n-r} \dfrac{n!}{(k+r)!(n-r-k)!} \dfrac{n!}{(n-k)!k!}$
$=(n+r)! \sum_{k=0}^{n-r} {{n}\choose{k+r}}{{n}\choose{n-k}}$
Differentiating left side gives $(n+r)!{{2n}\choose{n+r}}$
Giving the desired equality.