Let $A$ and $B$ be $C^*$-algebras and consider a $*$-homomorphism $\varphi: A \to B$. Then the biduals $A^{**}$ and $B^{**}$ carry natural $C^*$-structures (coming from the enveloping von Neumann algebra) so that the map $$\varphi^{**}: A^{**}\to B^{**}$$ is again a $*$-morphism.
If $\varphi$ is isometric (i.e. injective), it is easily verified (using general properties of adjoint maps on normed spaces) that $\varphi^{**}: A^{**}\to B^{**}$ is again isometric.
I'm now wondering if surjectivity of $\varphi$ implies surjectivity of $\varphi^{**}$.
We can't use the straightforward route: we have $\varphi$ surjective $\implies $ $\varphi^*$ injective but this does not allow us to conclude that $\varphi^{**}$ is surjective. I'm starting to think there may be a counterexample!
The map $\phi^{\ast\ast}$ is indeed surjective. First note that the image of $\phi^{\ast\ast}$ contains $B$, which is weak$^\ast$ dense in $B^{\ast\ast}$ by Goldstine's theorem. Moreover, as $\phi^{\ast\ast}$ is weak$^\ast$ continuous, its image is weak$^\ast$ closed by Proposition 1.16.2 of Sakai's $C^\ast$-Algebras and $W^\ast$-algebras. Thus it must equal $B^{\ast\ast}$.