If we consider a simple 1D cellular automaton (acting on a binary string) and record a value at a fixed position in the string, we can interpret the recorded sequence as a binary number.
Most simple deterministic cellular automata generate periodic sequences of binary digits which can be interpreted as rational numbers.
However, there are 'random' deterministic CA, such as elementary CA rule 30, discovered by S. Wolfram. Starting from a single point, it generates data which is random enough to be used as a random number generator. See this paper for more information.
Now, since this CA has perfectly deterministic (and simple) rules, what can we tell about numbers it generates at fixed string positions?
Since most of the 'randomness' happens to the right side, let's look at the numbers we get at positions from the center to the right, starting from the topmost $1$ in each case (see the figure). All the numbers are considered to have zero integer parts and are converted to the decimal notation from binary:
$$a_0=0.8623897839473840486408002460867511281\dots$$
$$a_1=0.6619938131535679545367590611375473724\dots$$
$$a_2=0.7759963493462055882598583123808285092\dots$$
$$a_3=0.7313593429560050953478343145780694591\dots$$
$$a_4=0.8215879687059052475349289186091204860\dots$$
$$a_5=0.6314259431664999548181068438831291123\dots$$
$$a_6=0.8079966728503828647993510584534608703\dots$$
Can we prove/disprove that these numbers are irrational? Trancendental? Or can we only guess based on direct experiments? What about other such 'random' cellular automata?

The answer itself isn't very surprising or illuminating so sorry :/
First, since you've posted a picture of rule 30, discussed here, we will be considering number generation from that CA only.
Second, recall the definition of an irrational number,
Corollary 1:
Proof: Assume that the decimal expansion does repeat. Then the number is, by definition, rational. Thus, our assumption is false, and the corollary is true.
Now it's been proven by Jen 1990 that with the initial state of a single black cell, the sequence of colors attained in any two adjacent cells is not periodic. Corroborated by Gray 2003.
So if we define a sequence of numbers using the cell states generated by rule 30, then the digits will not be periodic. By Corollary 1, If the digits are not periodic, then the number is irrational.
So let's look at your question(s)
We can prove that these numbers are irrational, for rule 30.
Almost surely.
Any cellular automata with non-periodic evolution will also generate irrational numbers.