For every $n$, can we find a number field of degree $n$ whose ring of integers is a unique factorization domain?
As a Dedekind domain is a UFD iff it is a PID, this is equivalent to asking the following: For every $n$, can we find a number field of degree $n$ with class number 1.
It seems that the answer is not known, see here. It has not even been proven that there are infinitely many number fields with class number $1$. It is tempting to look for a family of number fields, like for cyclotomic fields $\Bbb Q(\zeta_n)$ of degree $\phi(n)$. However, there the class number is equal to $1$ only for some "small" $n$, i.e., we have $n\le 90$. And, of course, $\phi(n)$ does not cover all positive integers.