Labeling the (p,q,r)-pretzel knot with transpositions from S4

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For what values of p,q, and r, can the (p,q,r)-pretzel knot be labeled with transpositions from $S_4$? I'm kind of stuck on how to approach this one. All I've got so far is that there are six transpositions in $S_4$ so I'm assuming there have to be at least six strands. Any help would be greatly appreciated!