Let PQR be a right angled isosceles triangle right angled at P (2,1). If equation of line QR is $2x+y=3$, find combined equation of pair of lines PQ and PR.
Let PQR be a right angled isosceles triangle right angled at P (2,1). If equation of line QR is $2x+y=3$, equations of PQ&PR
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Let $Q=(v,w),\ R=(x,y)$ so that $w=3-2v,\ y=3-2x.$ We want a right angle $QPR$ where $P=(2,1),$ so the dot product of the vectors $PQ=(v-2,w-1)$ and $PR=(x-2,y-1)$ is zero. Replacing $w,y$ in terms of $v,x$ in this dot product, and solving when it is zero for $v$ in terms of $x$ gives $$v=\frac{6x-8}{5x-6}.$$ Now since the triangle is isosceles, we need equal squared lengths for segments $PQ,PR$ which means $$(v-2)^2+(w-1)^2-(x-2)^2-(y-1)^2=0, \tag{1}$$ and if we replace things all in terms of $x$ and factor the result (maple is a help here), we get a fraction whose denominator is $(5x-6)^2$ and whose numerator has two linear factors $(5x-8)(5x-4)$ and a third factor which is quadratic irreducible (no real roots). Now we can rule out $x=6/5$ since it leads to $y=3-2(6/5)=3/5$, and then this point lies on the line through the origin and the right angle $P$, so cannot be a solution. This leaves two possible values $4/5,\ 8/5$ for $x$. (That there are two is because in naming the other two points $Q,R$ the names could be switched.)
Thus we now know the points $Q,R$ are in one or the other order $(4/5,7/5),\ (8/5,-1/5).$ It's now routine to get the two equations for lines $PQ,PR$ as $$x+3y-5=0,\quad 3x-y=5=0,$$ and if by the phrase of the question the "combined equation" is that which holds when a point is on the union of the two lines, one can form the product of the two left sides here and set it to zero.
The equation of any straight line passing through $P(2,1)$ can be written as $$\frac{y-1}{x-2}=m$$ where $m$ is the gradient/slope
Now as $\angle RPQ=90^\circ$ and $|PQ|=|RP|$
Using Isosceles Triangles have Two Equal Angles, $\displaystyle \angle PQR=\angle QRP=45^\circ$
If the angle between two lines with slope $m_1,m_2$ is $\phi$
$\displaystyle\tan\phi=\left|\frac{m_1-m_2}{1+m_1m_2}\right|$
In our case, $\displaystyle \phi=45^\circ$
we can set $m_1=m$(to be determined) and the $m_2,$ the gradient of $\displaystyle QR:2x+y=3\iff y=-2x+3$ is $-2$