I am new to Mathematica and am trying to check if the following matrix is positive definite with the program. The answer is supposed to be yes because $x > 0$ and $y > 0$ but I don't know how to add this into the function.

I know it is positive definite but I'm trying to use Mathematica to show that it is positive definite.
Yes, it is positive definite. One of several equivalent necessary and sufficient conditions is $q_{22}>0$ and $\det Q>0$.Note that $\det Q=48(x^6+x^2y)$.