Minimal number of nodes to connect a given set of nodes

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Let $G=(V,E)$ be an undirected graph and let $U \subset V$. Is there an algorithm that could find a minimal set of nodes that need to be added to $U$ so that the subgraph generated by the added nodes and nodes in $U$ is connected?

I know that such a set of added nodes is not usually unique. If finding such a set is very slow or almost impossible in big graphs, is there a way to a find such a set that it is quite close to being minimal?

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This is known as the Steiner tree problem. Note that minimizing vertices or edges is the same, since the number of vertices of a steiner tree is $e+1-c$ (where $c$ is the number of connected components in the graph induced by $|U|$, and not counting edges between vertices of $U $)

This is a NP-hard problem, but you can find some good approximation results (see the link)