I have taken the 12th problem of this pdf, do you know any way to resolve it without using brute force?
Simply I have to replace '*' of this multiplication below with correct digits, in order to have the factors corrected.
$$\begin{alignedat}{2}*&*4&&\,\times{}\\ &**&&={}\\\hline 44&*4&& \end{alignedat} $$
Each '*' can be a different digit.
The most straightforward way I can think of is to consider all ten possibilities for the * in 44*4, factor each into primes, and see which ones have prime factors that can recombine into a two-digit number and a three-digit number that ends in a $4$:
$$\begin{align} 4404&=2\cdot2\cdot3\cdot367\\ 4414&=2\cdot2207\\ 4424&=2\cdot2\cdot2\cdot7\cdot79\\ 4434&=2\cdot3\cdot739\\ 4444&=2\cdot2\cdot11\cdot101\\ 4454&=2\cdot17\cdot131\\ 4464&=2\cdot2\cdot2\cdot2\cdot3\cdot3\cdot31\\ 4474&=2\cdot2237\\ 4484&=2\cdot2\cdot19\cdot59\\ 4494&=2\cdot3\cdot7\cdot107 \end{align}$$
There is more than one answer:
However, this seems a bit brute-forcey. In particular, how do we know $2207$ and $2237$ are primes? If you're trying to do everything by hand (which I didn't!), you've got your work cut out for you.