Is it true for any $N\geq 1$, there is a value $f(N)$ such that for any integer $x\geq f(N)$ the integers $x+1,x+2,x+3,\ldots ,x+N$ are always multiplicatively independent (i.e. the relation $(x+1)^{e_1}(x+2)^{e_2}\ldots (x+N)^{e_N}=1$ with the $e_k\in{\mathbb Z}$ is possible only when all of the $e_k$'s are zero).
I have checked this for $N=2,3$. Let $f(N)$ be the smallest such thing described above. We have $f(2)=1$ because $x$ and $x+1$ are always coprime.
For $N=3$, we have $f(3)=2$. This can be checked as follows :
Suppose that $x$ is even. Let $2^t$ be the largest power of $2$ that divides $x+2$. Then $x+1,\frac{x+2}{2^t},x+3$ are mutually coprime odd integers and the result follows.
Next, suppose that $x\equiv 1 \ ({\mathsf{mod}}\ 4)$. Let $2^r$ be the largest power of $2$ that divides $x+3$. Then $r\geq 2$, $\frac{x+1}{2},x+2,\frac{x+3}{2^t}$ are mutually coprime odd integers and the result follows.
Finally, suppose that $x\equiv 3 \ ({\mathsf{mod}}\ 4)$. Let $2^s$ be the largest power of $2$ that divides $x+1$. Then $s\geq 2$, $\frac{x+1}{2^s},x+2,\frac{x+3}{2}$ are mutually coprime odd integers and the result follows.
Most certainly.
Assuming this Lemma, let's prove the existence of $f(N)$ for each $N \ge 1$. I do this by proving the existence of $f(N,k)$ for each $N,k \ge 1$, defined to be the least positive integer such that $x_1,\dots,x_N$ are multiplicatively independent if $f(N,k) \le x_1 < x_2 < \dots < x_N \le x_1+k-1$. (Note $f(N) = f(N,N)$.) We induct on $N$ to show $f(N,k)$ exists for all $k$. For $N=1$, the result is immediate. Suppose $f(N-1,k)$ exists for all $k$. Define $f(N,k) = \max(f(N-1,k),g(N,k))$. Take $x_1,\dots,x_N$ with $f(N,k) \le x_1 < x_2 < \dots < x_N \le x_1+k-1$. Then, by definition of $g(N,k)$, there is a prime $p$ dividing exactly one of $x_1,\dots,x_m$, say $x_j$. So, if $x_1^{e_1}\dots x_N^{e_N} = 1$ for $e_1,\dots,e_N \in \mathbb{Z}$, we must have $e_j = 0$. But since $y_1,\dots,y_{N-1} := x_1,\dots,x_{j-1},x_{j+1},\dots,x_N$ satisfy $f(N-1,k) \le y_1 < \dots < y_{N-1} \le y_1+k-1$, we know that $y_1,\dots,y_{N-1}$ are multiplicatively independent, completing the inductive step.
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Here is a reference, found by QC_QAOA, for that Tijdeman result and its proof. I wonder if there's an easier proof for just that $\liminf_{n \to \infty} a_{n+1}-a_n = +\infty$.