So, my textbook explains how to find the volume of a paralelpiped using $\mathbf{A} \cdot (\mathbf{B} \times \mathbf{C})$. Makes sense, basically. But, when I go to do problems some combinations produce negative volumes. Example: $P(-2,1,0),\space Q(2,3,2),\space R(1,3,-1),\space S(3,6,1)$ and I compute the following vectors: $\mathbf{PQ}=<4,2,2>\space\mathbf{PR}=<3,3-1>\space\mathbf{PS}=<5,5,1>$.
However, this creates a little problem: $\mathbf{PR}\cdot(\mathbf{PQ}\times\mathbf{PS})=-16$ whereas $\mathbf{PQ}\cdot(\mathbf{PR}\times\mathbf{PS})=16$.
I know that the volume is 16, but where does the negative come from? What does it mean? How do I prevent, predict or use this behavoir?
Thanks!
The formula you are using gives in fact a signed volume, i.e. it can also be negative. The idea is the following: imagine for example a cube (with positive volume), now if you reduce the length of one of its edges, the volume will become smaller and smaller, until you get to $0$. Now, you can reduce the length of the edge further (making it become "negative", in some sense), and it makes sense that the volume would get smaller too, and thus negative. You can get the "correct", positive volume you're looking for simply by taking the absolute value of what you found, as SantiagoCanez remarked in the comments.
A side note: the most correct point of view for this is probably the one dealing with orientations, and obviously linear algebra but you'll learn about them only later (and probably only if you'll study maths or a related subject).