Permutation and Combinations on Calculator

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How can I calculate permutation and combinations on a calculator using nPr and nCr? I want to compute with nPr and nCr buttons.

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Depends what calculator. You can use the formulas $$ nCr = \frac{n!}{(n-r)!r!}$$ and $$ nPr = \frac{n!}{(n-r)!}$$ if you have access to a factorial.