I'm reflecting about mathematical objects as numbers, sets/classes, graphs and so on.
Any class correspond to a predicate in one variable and any graph correspond to a predicate in two variables. There are exceptions for the correspondence in the other direction since "$x\notin x$" doesn't correspond to a class and "$R(x,y)\leftrightarrow \neg R(y,y)$" normally doesn't correspond to a graph.
In my opinion it seems to exist possible mathematical objects for each $n$ and predicates $p(x_1,...,x_n)$ with similar semi-correspondence. My intuition about this is that these objects are built upon the idea of simplex and I would like to know if it is true that
It always exists predicates $p_1,\dots,p_{n}$ such that
$p(x_1,\dots,x_n)\leftrightarrow\wedge_{i=1}^{n}p_i(x_1,\dots,x_{i-1},x_{i+1},\dots,x_n)$
Before addressing your actual question, let me point out that there are serious issues with your motivating examples.
First of all, "$x\not\in x$" does correspond to a class - namely, the universal class (in ZFC at least; a smaller class under NF). Every formula defines a class; that's what classes are, really.
Meanwhile, the issue with the $R$ you describe is that you haven't really (but see the bulletpoint below) defined a relation, but rather written a property a relation may or may not have. That's the issue with a self-referential "definition" (note that $R$ occurs on both sides of the expression you've written: when defining an object you need to show that it $(1)$ holds of something and $(2)$ only holds of one thing, and you haven't done that. Actually, this is something you have to do with any purported definition, but self-reference in particular makes $(1)$ especially nontrivial. (See also my old answer here.)
These issues, however, don't actually impact your question (although they probably do impact its motivation).
Your question has an easy negative answer: let $p(x_1,...,x_n)$ hold iff for some $i\in\{1,...,n\}$ we have $x_i=0$. Then for any tuple of objects $a_1,...,a_n$ we have $$p(0,a_2,a_3,...,a_n)\wedge p(a_1,0,a_3,...,a_n)\wedge...\wedge p(a_1,a_2,..., 0).$$ So the desired $p_i$s would have to satisfy $$p_1(a_2,a_3,...,a_n)\wedge p_2(a_1,a_3,...,a_n)\wedge ...\wedge p_n(a_1,a_2,..., a_{n-1})$$ for every tuple of objects $a_1,a_2,...,a_n$. But then we have $$\bigwedge_{i\in\{1,...,n\}}p_i(a_1,..., a_{i-1}, a_{i+1}, ..., a_n)$$ for every tuple of objects $a_1,..., a_n$, which is a problem since e.g. $\neg p(1,1,...,1)$.
Incidentally, it's easy to see that the only possible candidate $p_i$s, for a given $p$, are $$p_i(a_1,..., a_{n-1})\iff \exists b(p_i(a_1, a_2,..., a_{i-1}, b, a_i, ..., a_n)).$$